Name of the submitted project or idea (in English or both English and your language)
Novel solution of plant-based protein production platform of Growth Factors making the Cultivated Meat commercially viable.
URL of a video introducing the work（under 5 minutes）
Detailed explanation of the submitted project or idea (in English or both English and your language)
The expected increase in world population, along with the dwindling natural resources, will place a significant burden on food suppliers. Therefore, we must develop new strategies that will support a decrease in the farming industry. Cellular agriculture (Cell-Ag) refers to the growth of tissues outside the body by tissue engineering. Particular cells are assembled on a scaffold with serum in an environment that promotes growth. Cell-Ag products have fewer environmental impacts than conventional methods, as well as safer, purer products and a more consistent supply. Livestock husbandry places a significant burden on our environmental resources by causing land erosion, increasing levels of greenhouse gases, water pollution, heavy water use, overuse of antibiotics that can increase the evolution of antibiotic-resistant bacteria, and biodiversity loss. The livestock sector is responsible for 14.5% of total greenhouse gas emissions and uses 23% of globally-available freshwater. These deleterious environmental effects can be alleviated by several Cell-Ag products, such as cultivated meat (CM), dairy, eggs, and leather, all of which depend on livestock. One promising avenue of Cell-Ag is CM, which is much more sustainable and eco-friendly than traditional livestock and is estimated to cut the climate impact of meat by 92% by reducing air pollution by up to 93%, using up to 95% less land, and 78% less water. BioBetter is going to revolutionize the supply of ingredients required for the Cell-Ag industry in a green, environmentally friendly way. A significant hurdle for cultivated food technologies is its dependence on expensive Growth Factors (GFs). GFs such as Insulin, are proteins that play a critical role in regulating cell proliferation and differentiation.
Existing GFs production technologies and infrastructures are complex and expensive. Furthermore, these technologies are unsuitable for producing GFs in sufficient volumes and at low enough costs to support commodity-scale production. It is impractical and expensive to attempt and reach the required manufacturing capacities using current fermentation technologies.
cultivated meat, cellular agriculture, plant bioreactor
If you have a website for your submitted project or idea, please provide the URL
Special Prize Question 1: How does your project or idea make use of local resources, such as materials and knowledge, to tackle its challenge?
BioBetter is located in the northernmost part of Israel and employs local scientists and agricultural experts.
Special Prize Question 2: How does your project or idea sustain its activities through the involvement of the local community?
Our pilot will include recombinant tobacco grown in open fields in Northern Israel. Later on, we envision the repurposing of existing tobacco fields to grow BioBetter's recombinant protein-producing plants. Since this part of the protein production process does not require any complicated or expensive machinery or expertise, it will be accessible to tobacco farmers worldwide.
Special Prize Question 3: How does your project or idea eliminate waste or pollution while regenerating natural resources?
Currently, 77% of global agricultural land is used to produce livestock feed, causing land erosion, deforestation, and biodiversity loss. This immense area of 40 million km2 provides only 18% of the global calorie supply and is water- and fertilizer-use intensive. Therefore, Cell-Ag has the potential to significantly reduce environmental damage. One promising avenue of Cell-Ag is CM, which is much more sustainable and eco-friendly than traditional livestock and is estimated to cut the climate impact of meat by 92% by reducing air pollution by up to 93%, using up to 95% less land, and 78% less water. The transgenic tobacco plants become self-sustained, renewable energy-driven, xenon-free, animal-free “bioreactors”. They produce and store the protein, maintaining sterility and homeostasis until harvest. By using tobacco plants that are propagated through seeds and grown in open fields, Capex and Opex of protein production are dramatically reduced.